IL-17 in systemic lupus erythematosus
نویسندگان
چکیده
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies and the formation of immune complexes that can damage multiple tissues, organs and systems. IL‐17 is a proinflammatory cytokine that plays an important role in several autoimmune diseases including SLE. The expression of IL‐17 is elevated in both SLE patients and in lupus‐prone mice, and it is positively correlated with disease activity. IL‐17 also appears to participate in the development of several SLE complications. In this article, we provide an overview and an update of the role of IL-17 in SLE.
منابع مشابه
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تاریخ انتشار 2016